What Do You Give After Atropine?

What is action of atropine?

Pharmacodynamics.

Atropine reduces secretions in the mouth and respiratory passages, relieves the constriction and spasm of the respiratory passages, and may reduce the paralysis of respiration, which results from actions of the toxic agent on the central nervous system..

At what heart rate do you give atropine?

Atropine: The first drug of choice for symptomatic bradycardia. The dose in the Bradycardia ACLS algorithm is 0.5mg IV push and may repeat up to a total dose of 3mg. Dopamine: Second-line drug for symptomatic bradycardia when atropine is not effective. Dosage is 2-20 micrograms/kg/min infusion.

How is atropine poisoning treated?

Specific treatmentGive physostigmine salicylate, 0.5–1 mg intravenously slowly over 5 minutes, with ECG monitoring.Repeat as needed to total dose of no more than 2 mg.

How fast do you give atropine?

Atropine should be administered by rapid IV push and may be repeated every 3-5 minutes, to a maximum dose of 3 mg.

What happens if you give too much atropine?

Excess doses of atropine sulfate may cause side effects such as palpitations, dilated pupils, difficulty swallowing, hot dry skin, thirst, dizziness, restlessness, tremor, fatigue, and problems with coordination.

Why would you give atropine?

Atropine is a prescription medicine used to treat the symptoms of low heart rate (bradycardia), reduce salivation and bronchial secretions before surgery or as an antidote for overdose of cholinergic drugs or mushroom poisoning. Atropine may be used alone or with other medications.

When should atropine be used?

Atropine is the first-line therapy (Class IIa) for symptomatic bradycardia in the absence of reversible causes. Treatments for bradydysrhythmias are indicated when there is a structural disease of the infra-nodal system or if the heart rate is less than 50 beats/min with unstable vital signs.

Why does atropine cause bradycardia initially?

Atropine acts on the M2 receptors of the heart and antagonizes the activity of acetylcholine. It causes tachycardia by blocking vagal effects on the sinoatrial node. … Intake of acetylcholine in axoplasm is prevented and the presynaptic nerve releases more acetylcholine into the synapse that initially causes bradycardia.

How much atropine do you give?

The dosing for Atropine is 0.5 mg IV every 3-5 minutes as needed, and the maximum total dosage for administration is 3 mg. Atropine should be avoided with bradycardia caused by hypothermia and, in most cases, it will not be effective for Mobitz type II/Second-degree block type 2 or complete heart block.

When should you not take atropine?

Who should not take Atropine SULFATE Syringe?myasthenia gravis.a skeletal muscle disorder.high blood pressure.chronic heart failure.a change in saliva secretion.reflux esophagitis.or inflammation of the esophagus from backflow of stomach acid.hiatal hernia.More items…

How long does atropine take to wear off?

The blurred vision, caused by the atropine, will last for approximately seven days after the last instillation. The dilated pupil may remain for as long as 14 days. Are there any side effects?

Does atropine slow heart rate?

Atropine has complex effects on heart rate: At low doses, atropine blocks M1 acetylcholine receptors in the parasympathetic ganglion controlling the SA node. This decreases heart rate (Bernheim 2004). At higher doses, atropine also blocks M2 acetylcholine receptors on the myocardium itself.

Why Atropine is given in OP poisoning?

Atropine is given to poisoned patients to block muscarinic overstimulation. However, neuromuscular blocking agents (nicotinic acetylcholine receptor antagonists) are not currently used to prevent nicotinic overstimulation 57.

What are atropine drops used for?

Ophthalmic atropine is used before eye examinations to dilate (open) the pupil, the black part of the eye through which you see. It is also used to relieve pain caused by swelling and inflammation of the eye.

How does atropine cause bradycardia?

Background—Low-dose atropine causes bradycardia either by acting on the sinoatrial node or by its effects on central muscarinic receptors increasing vagal activity.

Why does atropine not work in transplanted heart?

After a heart transplant, patients will also have no response of heart rate to carotid sinus massage or drugs such as atropine, which act by blocking the action of acetylcholine at parasympathetic sites.

What do you give after atropine for bradycardia?

Epinephrine. Epinephrine infusion may be used for patients with symptomatic bradycardia or hypotension after atropine or pacing fails (Class IIb). Begin the infusion at 2 to 10 μg/min and titrate to patient response.

What is atropine used for in emergency situations?

Although atropine treats bradycardia (slow heart rate) in emergency settings, it can cause paradoxical heart rate slowing when given at very low doses (i.e. <0.5 mg), presumably as a result of central action in the CNS.