What are the side effects of long term use of metformin?
More common side effects of metforminheartburn.stomach pain.nausea or vomiting.bloating.gas.diarrhea.constipation.weight loss.More items…•.
Can diabetes cause liver damage?
Type 2 diabetes is associated with a large number of liver disorders including elevated liver enzymes, fatty liver disease, cirrhosis, hepatocellular carcinoma, and acute liver failure. In addition, there is an unexplained association with HCV.
Is metformin harmful to the liver?
Metformin is not considered intrinsically hepatotoxic. In fact, metformin may be beneficial in patients with nonalcoholic fatty liver disease (1) and chronic hepatitis C (3). Metformin is only contraindicated in patients with advanced cirrhosis because it heightens the risk of developing lactic acidosis (4).
Can metformin damage liver and kidneys?
Can long-term metformin use cause kidney damage? Metformin does not cause kidney damage. The kidneys process and clear the drug out of your system via urine. If your kidneys are not functioning properly, metformin can build up in your system and cause a condition called lactic acidosis.